I'm running the same setup and thinking about a few of the same questions.
1. Try to setup a UI and work in performance mode, then your machine doesn't have to render everything in the project (this gives me a pretty considerable performance boost)
2. From what I've read here, the Quadro cards all come from one company, so they can be a bit more reliable, but something to keep in mind we're in-between upgrade cycles right now on the two lines (Geforce & Quadro). The Geforce GTX680m is about to released with the new Kepler architecture, while the Quadro line is still using the Fermi architecture and won't be upgraded till early next year. On paper this means that the soon to be released (like it should start rolling out now) Kepler based 680m has more power than the current Fermi based Quadro 5000m (don't quote me 100%, but that's what I've read in benchmarks).
With that in mind I guess it depends on when you plan on upgrading your machine. I know I'll be upgrading shortly, so I will most likely grab a machine with a 680m in it (probably a Sager). If you were ok waiting till Spring 2013, then you'd be able to see benchmarks on the Kepler based Quadro cards. Just something to keep in mind.
In regards to aero:
The link below is an extremely helpful link for setting up your computer for audio production, but a lot of it is applicable for Touch, as its just ways to get the most out of your machine (big thanks to PreSonus for this!)http://www.presonus.com/community/learn ... for-vista/
The link says Vista, but everything is applicable to Windows 7.